Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf>

• المؤلفون الرئيسيون: Jongkonporn Phetcharawetch, Nolan M. Betterley, Vichai Reutrakul, Darunee Soorukram, Pawaret Leowanawat, Chutima Kuhakarn
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2022
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Environmental Science
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/76013

Direct and effective trifluoromethylthiolation of 2-alkynyl azidoarenes with silver(I) trifluoromethanethiolate (AgSCF3) has been developed for the construction of 3-((trifluoromethyl)thio)indoles. The trifluoromethylthiolation protocol is compatible with a broad substrate scope, providing a variety...