Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf>
Direct and effective trifluoromethylthiolation of 2-alkynyl azidoarenes with silver(I) trifluoromethanethiolate (AgSCF3) has been developed for the construction of 3-((trifluoromethyl)thio)indoles. The trifluoromethylthiolation protocol is compatible with a broad substrate scope, providing a variety...
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2022
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| الوصول للمادة أونلاين: | https://repository.li.mahidol.ac.th/handle/123456789/76013 |
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th-mahidol.760132022-08-04T15:39:53Z Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf> Jongkonporn Phetcharawetch Nolan M. Betterley Vichai Reutrakul Darunee Soorukram Pawaret Leowanawat Chutima Kuhakarn Mahidol University Biochemistry, Genetics and Molecular Biology Chemistry Environmental Science Direct and effective trifluoromethylthiolation of 2-alkynyl azidoarenes with silver(I) trifluoromethanethiolate (AgSCF3) has been developed for the construction of 3-((trifluoromethyl)thio)indoles. The trifluoromethylthiolation protocol is compatible with a broad substrate scope, providing a variety of 3-((trifluoromethyl)thio)indoles in moderate to good yields within one step, open-air, and short reaction time. 2022-08-04T08:05:23Z 2022-08-04T08:05:23Z 2021-10-01 Article Journal of Fluorine Chemistry. Vol.250, (2021) 10.1016/j.jfluchem.2021.109878 00221139 2-s2.0-85114303231 https://repository.li.mahidol.ac.th/handle/123456789/76013 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85114303231&origin=inward |
| institution |
Mahidol University |
| building |
Mahidol University Library |
| continent |
Asia |
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Thailand Thailand |
| content_provider |
Mahidol University Library |
| collection |
Mahidol University Institutional Repository |
| topic |
Biochemistry, Genetics and Molecular Biology Chemistry Environmental Science |
| spellingShingle |
Biochemistry, Genetics and Molecular Biology Chemistry Environmental Science Jongkonporn Phetcharawetch Nolan M. Betterley Vichai Reutrakul Darunee Soorukram Pawaret Leowanawat Chutima Kuhakarn Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf> |
| description |
Direct and effective trifluoromethylthiolation of 2-alkynyl azidoarenes with silver(I) trifluoromethanethiolate (AgSCF3) has been developed for the construction of 3-((trifluoromethyl)thio)indoles. The trifluoromethylthiolation protocol is compatible with a broad substrate scope, providing a variety of 3-((trifluoromethyl)thio)indoles in moderate to good yields within one step, open-air, and short reaction time. |
| author2 |
Mahidol University |
| author_facet |
Mahidol University Jongkonporn Phetcharawetch Nolan M. Betterley Vichai Reutrakul Darunee Soorukram Pawaret Leowanawat Chutima Kuhakarn |
| format |
Article |
| author |
Jongkonporn Phetcharawetch Nolan M. Betterley Vichai Reutrakul Darunee Soorukram Pawaret Leowanawat Chutima Kuhakarn |
| author_sort |
Jongkonporn Phetcharawetch |
| title |
Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf> |
| title_short |
Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf> |
| title_full |
Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf> |
| title_fullStr |
Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf> |
| title_full_unstemmed |
Synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with AgSCF<inf>3</inf> |
| title_sort |
synthesis of 3-((trifluoromethyl)thio)indoles via trifluoromethylthiolation of 2-alkynyl azidoarenes with agscf<inf>3</inf> |
| publishDate |
2022 |
| url |
https://repository.li.mahidol.ac.th/handle/123456789/76013 |
| _version_ |
1763494392672288768 |