Fluoride-Catalyzed Nucleophilic Addition of PhSCF<inf>2</inf>SiMe<inf>3</inf> to Isatins: Synthesis of 3-(1′,1′-Difluoroalkyl)-3-hydroxyindolin-2-ones
© 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim The synthesis of 3-(1′,1′-difluoroalkyl)-3-hydroxyindolin-2-ones by employing α,α-difluoro-α-phenylsulfanyl-α-trimethylsilylmethane (PhSCF2SiMe3) as a gem-difluoromethylene building block is described. The reaction involves a fluoride-catalyzed...
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| Main Authors: | , , , , |
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| 格式: | Article |
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2019
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| 在線閱讀: | https://repository.li.mahidol.ac.th/handle/123456789/45511 |
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| 機構: | Mahidol University |