Curcumin and metformin synergistically modulate peripheral and central immune mechanisms of pain
Metformin is a well-tolerated antidiabetic drug and has recently been repurposed for numerous diseases, including pain. However, a higher dose of metformin is required for effective analgesia, which can potentiate its dose-dependent gastrointestinal side effects. Curcumin is a natural polyphenol and...
Saved in:
Main Authors: | Peththa Wadu Dasuni Wasana, Hasriadi, Chawanphat Muangnoi, Opa Vajragupta, Pranee Rojsitthisak, Pornchai Rojsitthisak, Pasarapa Towiwat |
---|---|
其他作者: | Metallurgy and Materials Research Institute Chulalongkorn University |
格式: | Article |
出版: |
2022
|
主題: | |
在線閱讀: | https://repository.li.mahidol.ac.th/handle/123456789/75389 |
標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
機構: | Mahidol University |
相似書籍
-
Curcumin diglutaric acid, a prodrug of curcumin reduces pain hypersensitivity in chronic constriction injury of sciatic nerve induced-neuropathy in mice
由: Thanchanok Limcharoen, et al.
出版: (2020) -
Improved antiallodynic, antihyperalgesic and anti-inflammatory response achieved through potential prodrug of curcumin, curcumin diethyl diglutarate in a mouse model of neuropathic pain
由: Thanchanok Limcharoen, et al.
出版: (2022) -
Molecular Insight into the Anti-Inflammatory Effects of the Curcumin Ester Prodrug Curcumin Diglutaric Acid In Vitro and In Vivo
由: Rianthong Phumsuay, et al.
出版: (2020) -
Curcumin and metformin synergistically modulate peripheral and central immune mechanisms of pain
由: Dasuni Wasana P.W.
出版: (2023) -
Physicochemical investigation of a novel curcumin diethyl γ-aminobutyrate, a carbamate ester prodrug of curcumin with enhanced anti-neuroinflammatory activity
由: Ponsiree Jithavech, et al.
出版: (2022)