Enhanced selective cytotoxicity of doxorubicin to breast cancer cells by methoxypolyethylene glycol conjugation via a novel beta-thiopropanamide linker

Enhanced selective cytotoxicity of doxorubicin to breast cancer cells by methoxypolyethylene glycol conjugation via a novel beta-thiopropanamide linker

© 2020 Elsevier Ltd Doxorubicin (DOX) is a chemotherapeutic agent that suffers from severe adverse effects due to non-selective cell cytotoxicity. This study designs a novel beta-thiopropanamide linker (A) which conjugates DOX with methoxypolyethylene glycol (mPEG) to sustain systemic drug release,...

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Main Authors: Wiwat Supasena, Chawanphat Muangnoi, Kemika Praengam, Tin Wui Wong, Guanyinsheng Qiu, Shengqing Ye, Jie Wu, Somboon Tanasupawat, Pornchai Rojsitthisak
其他作者: Jiaxing University
格式: Article
出版: 2020
主題:
Chemistry
Materials Science
在線閱讀:https://repository.li.mahidol.ac.th/handle/123456789/59927
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機構: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/59927

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