Cyclization of o-Alkynylisocyanobenzenes with 1,3-Dicarbonyl Compounds

• Main Authors: Kannika La-Ongthong, Natthapat Sawekteeratana, Jasarin Klaysuk, Darunee Soorukram, Pawaret Leowanawat, Vichai Reutrakul, Sucheewin Krobthong, Patompon Wongtrakoongate, Chutima Kuhakarn
• 其他作者: Mahidol University
• 格式: Article
• 出版: 2022
• 主題: Chemistry
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/73721

A facile and convenient reaction of o-alkynylisocyanobenzenes with various active-methylene compounds, including 1,3-diesters, 1,3-diketones, β-keto esters, and β-keto amides, under Brønsted basic conditions, has been developed. Diethyl malonate reacted smoothly with a collection of o-alkynylisocyan...