Synthesis of Indolo-and Benzothieno[2,3-b]quinolines by a Cascade Cyclization of o-Alkynylisocyanobenzene Derivatives

• Main Authors: Onnicha Khaikate, Natthamon Inthalaeng, Jatuporn Meesin, Kritchasorn Kantarod, Manat Pohmakotr, Vichai Reutrakul, Darunee Soorukram, Pawaret Leowanawat, Chutima Kuhakarn
• Other Authors: Mahidol University
• Format: Article
• Published: 2020
• Subjects: Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/50581

© 2019 American Chemical Society. A new synthetic approach for the synthesis of indolo[2,3-b]quinolines and benzothieno[2,3-b]quinolines has been developed by employing the freshly prepared o-alkynylisocyanobenzenes derived from o-alkynylformamide derivatives as substrates. The synthetic transformat...