The synthesis of wrightiadione via directed remote metalation

The application of directed remote metalation (DreM) and electrophilic substitution is reported for the synthesis of wrightiadione using N,N-diethylcarboxamide as a directed metalation group (DMG) and electrophilic group. The lithiation of N,N-diethylisoflavone-2′-carboxamide with LDA gave a carbani...

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Bibliographic Details
Main Authors: Nopporm Thasana, Somsak Ruchirawat
Other Authors: Chulabhorn Research Institute
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/20824
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