IBX/n-Bu<inf>4</inf>NBr/CH<inf>2</inf>Cl<inf>2</inf>-H<inf>2</inf>O: A new mild system for selective oxidation of secondary alcohols

• Main Authors: Chutima Kuhakarn, Krisada Kittigowittana, Manat Pohmakotr, Vichai Reutrakul
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/16295

A new alternative system for the chemoselective oxidation of secondary hydroxyl group to ketone with IBX/n-Bu4NBr in CH2Cl2-H2O has been developed. Under the reaction conditions, the secondary hydroxyl group was highly chemoselectively oxidized to the corresponding ketone, in moderate to good yields...