Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells

Synthesis, physicochemical properties, and protective effects of a novel water-soluble tetrahydrocurcumin-diglutaric acid prodrug on ethanol-induced toxicity in HepG2 cells

Purpose: Tetrahydrocurcumin (THC) is a major reductive metabolite of curcumin that exhibits potent antioxidant effects; however, its pharmacological activities are limited by its poor water solubility. To overcome this, tetrahydrocurcumin-diglutaric acid (TDG), a novel water-soluble ester prodrug of...

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Main Authors:	Nattapong Jongjitphisut, Rianthong Phumsuay, Worathat Thitikornpong, Paitoon Rashatasakhon, Chawanphat Muangnoi, Opa Vajragupta, Pornchai Rojsitthisak
其他作者:	Chulalongkorn University
格式:	Article
出版:	2022
主題:	Pharmacology, Toxicology and Pharmaceutics
在線閱讀:	https://repository.li.mahidol.ac.th/handle/123456789/75233
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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