Enhanced selective cytotoxicity of doxorubicin to breast cancer cells by methoxypolyethylene glycol conjugation via a novel beta-thiopropanamide linker
© 2020 Elsevier Ltd Doxorubicin (DOX) is a chemotherapeutic agent that suffers from severe adverse effects due to non-selective cell cytotoxicity. This study designs a novel beta-thiopropanamide linker (A) which conjugates DOX with methoxypolyethylene glycol (mPEG) to sustain systemic drug release,...
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Main Authors: | , , , , , , , , |
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Format: | Article |
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2020
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/59927 |
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