Enhanced selective cytotoxicity of doxorubicin to breast cancer cells by methoxypolyethylene glycol conjugation via a novel beta-thiopropanamide linker

© 2020 Elsevier Ltd Doxorubicin (DOX) is a chemotherapeutic agent that suffers from severe adverse effects due to non-selective cell cytotoxicity. This study designs a novel beta-thiopropanamide linker (A) which conjugates DOX with methoxypolyethylene glycol (mPEG) to sustain systemic drug release,...

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Bibliographic Details
Main Authors: Wiwat Supasena, Chawanphat Muangnoi, Kemika Praengam, Tin Wui Wong, Guanyinsheng Qiu, Shengqing Ye, Jie Wu, Somboon Tanasupawat, Pornchai Rojsitthisak
Other Authors: Jiaxing University
Format: Article
Published: 2020
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/59927
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