Synthesis of: N -alkyl-3-sulfonylindoles and N -alkyl-3-sulfanylindoles by cascade annulation of 2-alkynyl- N, N -dialkylanilines

• Main Authors: Jatuporn Meesin, Manat Pohmakotr, Vichai Reutrakul, Darunee Soorukram, Pawaret Leowanawat, Chutima Kuhakarn
• 其他作者: Mahidol University
• 格式: Article
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Chemistry
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/42050

© The Royal Society of Chemistry 2017. An efficient and metal-free approach to N-alkyl-3-sulfonylindoles and N-alkyl-3-sulfanylindoles from 2-alkynyl-N,N-dialkylanilines has been developed. In the presence of iodine and tert-butylhydroperoxide (TBHP), a variety of 2-alkynyl-N,N-dialkylanilines under...