Downregulation of LAT1 expression suppresses cholangiocarcinoma cell invasion and migration

• المؤلفون الرئيسيون: Keatdamrong Janpipatkul, Kanoknetr Suksen, Suparerk Borwornpinyo, Natee Jearawiriyapaisarn, Suradej Hongeng, Pawinee Piyachaturawat, Arthit Chairoungdua
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/33338

Currently, there is no effective treatment for cholangiocarcinoma (CCA), which is the most prevalent in the northeastern part of Thailand. A new molecular target for the treatment of CCA is, therefore, urgently needed. Although L-type amino acid transporter 1 (LAT1) is highly expressed in CCA cells,...