Total synthesis of (S)-(+)-melodorinol and (S)-(+)-acetylmelodorinol

(S)-(+)-Melodorinol and (S)-(+)-acetylmelodorinol have been synthesized by reacting the lithiated butenolide with 2,3-O-alkylidene-D-glyceraldehyde followed by successive elimination, hydrolysis, benzoylation and acetylation reactions.

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Bibliographic Details
Main Authors: Manat Pohmakotr, Patoomratana Tuchinda, Pornchai Premkaisorn, Attasit Limpongpan, Vichai Reutrakul
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/25382
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Institution: Mahidol University