γ-Regioselectivity of lithiated 2-buten-4-olide towards aromatic aldehydes: A simple synthesis of γ-arylidenebutenolides

• المؤلفون الرئيسيون: Manat Pohmakotr, Patoomratana Tuchinda, Pornchai Premkaisorn, Vichai Reutrakul
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/18292

Lithiated 2-buten-4-olide was found to react with aromatic aldehydes regioselectively at γ-position to provide 4-(1-aryl-1-hydroxymethyl)-2- buten-4-olides which could be readily converted into the corresponding (Z)- γ-arylidenebutenolides.