Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis
Proteases are ubiquitous in nature, whereas naturally occurring peptide ligases, enzymes catalyzing the reverse reactions of proteases, are rare occurrences. Here we describe the discovery of butelase 1, to our knowledge the first asparagine/aspartate (Asx) peptide ligase to be reported. This highly...
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| Main Authors: | , , , , , |
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| 其他作者: | |
| 格式: | Article |
| 語言: | English |
| 出版: |
2015
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| 在線閱讀: | https://hdl.handle.net/10356/79260 http://hdl.handle.net/10220/38787 |
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| 機構: | Nanyang Technological University |
| 語言: | English |