Genetic determinants in hla and cytochrome p450 genes in the risk of aromatic antiepileptic-induced severe cutaneous adverse reactions

• المؤلفون الرئيسيون: Ali Fadhel Ahmed, Chonlaphat Sukasem, Majeed Arsheed Sabbah, Nur Fadhlina Musa, Dzul Azri Mohamed Noor, Nur Aizati Athirah Daud
• مؤلفون آخرون: Ramathibodi Hospital
• التنسيق: مقال
• منشور في: 2022
• الموضوعات: Medicine
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/78718
• المؤسسة: Mahidol University

Adverse drug reaction (ADR) is a pressing health problem, and one of the main reasons for treatment failure with antiepileptic drugs. This has become apparent in the event of severe cutaneous adverse reactions (SCARs), which can be life-threatening. In this review, four hypotheses were identified to...