Are bet inhibitors yet promising latency-reversing agents for hiv-1 reactivation in aids therapy?

• المؤلفون الرئيسيون: Thanarat Salahong, Christian Schwartz, Rungroch Sungthong
• مؤلفون آخرون: Dynamique des Interactions Hôte Pathogène (DIHP)
• التنسيق: Review
• منشور في: 2022
• الموضوعات: Immunology and Microbiology; Medicine
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/77275
• المؤسسة: Mahidol University

AIDS first emerged decades ago; however, its cure, i.e., eliminating all virus sources, is still unachievable. A critical burden of AIDS therapy is the evasive nature of HIV-1 in face of host immune responses, the so-called “latency.” Recently, a promising approach, the “Shock and Kill” strategy, wa...