Measurement of gene amplifications related to drug resistance in Plasmodium falciparum using droplet digital PCR

• Main Authors: Suttipat Srisutham, Kanokon Suwannasin, Rungniran Sugaram, Arjen M. Dondorp, Mallika Imwong
• 其他作者: Faculty of Tropical Medicine, Mahidol University
• 格式: Article
• 出版: 2022
• 主題: Immunology and Microbiology; Medicine
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/77184
• 機構: Mahidol University

Background: Copy number variations (CNVs) of the Plasmodium falciparum multidrug resistance 1 (pfmdr1), P. falciparum plasmepsin2 (pfplasmepsin2) and P. falciparum GTP cyclohydrolase 1 (pfgch1) genes are associated with anti-malarial drug resistance in P. falciparum malaria. Droplet digital PCR (ddP...