Measurement of gene amplifications related to drug resistance in Plasmodium falciparum using droplet digital PCR

• المؤلفون الرئيسيون: Suttipat Srisutham, Kanokon Suwannasin, Rungniran Sugaram, Arjen M. Dondorp, Mallika Imwong
• مؤلفون آخرون: Faculty of Tropical Medicine, Mahidol University
• التنسيق: مقال
• منشور في: 2022
• الموضوعات: Immunology and Microbiology; Medicine
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/77184
• المؤسسة: Mahidol University

Background: Copy number variations (CNVs) of the Plasmodium falciparum multidrug resistance 1 (pfmdr1), P. falciparum plasmepsin2 (pfplasmepsin2) and P. falciparum GTP cyclohydrolase 1 (pfgch1) genes are associated with anti-malarial drug resistance in P. falciparum malaria. Droplet digital PCR (ddP...