Neurorescue effects of frondoside a and ginsenoside rg3 in c. Elegans model of parkinson’s disease

• Main Authors: Pawanrat Chalorak, Tanatcha Sanguanphun, Tanapol Limboonreung, Krai Meemon
• Other Authors: King Mongkut's Institute of Technology Ladkrabang
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76071
• Institution: Mahidol University

Parkinson’s disease (PD) is a currently incurable neurodegenerative disorder characterized by the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta and αsynuclein aggregation. Accumulated evidence indicates that the saponins, especially from ginseng, have neuroprotective e...