Synthesis and characterization of andrographolide derivatives as regulators of βapp processing in human cells

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic processing of the β-amyloid precursor protein (βAPP), α-...

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Main Authors: Arpita Dey, Ran Chen, Feng Li, Subhamita Maitra, Jean Francois Hernandez, Guo Chun Zhou, Bruno Vincent
其他作者: Université de Montpellier
格式: Article
出版: 2022
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在線閱讀:https://repository.li.mahidol.ac.th/handle/123456789/75897
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機構: Mahidol University