Synthesis and characterization of andrographolide derivatives as regulators of βapp processing in human cells
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder, one of the main characteristics of which is the abnormal accumulation of amyloid peptide (Aβ) in the brain. Whereas β-secretase supports Aβ formation along the amyloidogenic processing of the β-amyloid precursor protein (βAPP), α-...
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Main Authors: | , , , , , , |
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格式: | Article |
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2022
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在線閱讀: | https://repository.li.mahidol.ac.th/handle/123456789/75897 |
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機構: | Mahidol University |