Enhancement of Lipolysis in 3T3-L1 Adipocytes by Nitroarene Capsaicinoid Analogs

• المؤلفون الرئيسيون: Thanet Laolob, Nuntavan Bunyapraphatsara, Neti Waranuch, Sutatip Pongcharoen, Wikorn Punyain, Sirirat Chancharunee, Krisada Sakchaisri, Jaturong Pratuangdejkul, Sumet Chongruchiroj, Filip Kielar, Uthai Wichai
• مؤلفون آخرون: Naresuan University
• التنسيق: مقال
• منشور في: 2022
• الموضوعات: Agricultural and Biological Sciences; Medicine; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/75808
• المؤسسة: Mahidol University

Transient receptor potential vanilloid 1 (TRPV1) activation by capsaicin binding increased intracellular calcium influx and stimulated adipocyte-to-adipocyte communication, leading to lipolysis. Generally, enhancement of π-stacking capabilities improves certain binding interactions. Notably, nitroar...