Genetic diversity and lack of artemisinin selection signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion

• المؤلفون الرئيسيون: Miao, Miao, Wang, Zenglei, Yang, Zhaoqing, Yuan, Lili, Parker, Daniel M., Chaturong Putaporntip, Somchai Jongwutiwes, Xangsayarath, Phonepadith, Pongvongsa, Tiengkham, Moji, Hazuhiko, Tuong, Trinh Dinh, Abe, Tomoko, Nakazawa, Shusuke, Kyaw, Myat Phone, Yan, Guiyun, Jeeraphat Sirichaisinthop, Jetsumon Sattabongkot, เจตสุมน สัตตบงกช, Mu, Jianbing, Su, Xin-zhuan, Kaneko, Osamu, Cui, Liwang
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: Genetic; Plasmodium falciparum; Open Access article
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/752
• المؤسسة: Mahidol University

The recent detection of clinical Artemisinin (ART) resistance manifested as delayed parasite clearance in the Cambodia-Thailand border area raises a serious concern. The mechanism of ART resistance is not clear; but the P. falciparum sarco/endoplasmic reticulum Ca(2+)-ATPase (PfSERCA or PfATP6)...