Suppression of PI3K/Akt/mTOR pathway in chrysoeriol-induced apoptosis of rat C6 glioma cells

Suppression of PI3K/Akt/mTOR pathway in chrysoeriol-induced apoptosis of rat C6 glioma cells

Chrysoeriol, a dietary methoxyflavonoid which is found in tropical medicinal plants, has been shown to have antioxidant, anti-inflammatory, and antineoplastic properties. The present study aimed to investigate the effects of chrysoeriol and its related mechanisms in rat C6 glioma cells. Cell viabili...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Suppanut Wongkularb, Tanapol Limboonreung, Patoomratana Tuchinda, Sukumal Chongthammakun
مؤلفون آخرون:	King Mongkut's Institute of Technology Ladkrabang
التنسيق:	مقال
منشور في:	2022
الموضوعات:	Biochemistry, Genetics and Molecular Biology
الوصول للمادة أونلاين:	https://repository.li.mahidol.ac.th/handle/123456789/73542
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة

Suppression of PI3K/Akt/mTOR pathway in chrysoeriol-induced apoptosis of rat C6 glioma cells
بواسطة: Wongkularb S.
منشور في: (2023)

Chrysoeriol mediates mitochondrial protection via PI3K/Akt pathway in MPP<sup>+</sup> treated SH-SY5Y cells
بواسطة: Tanapol Limboonreung, وآخرون
منشور في: (2020)

Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy
بواسطة: Wu, Y.-T., وآخرون
منشور في: (2011)

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
بواسطة: Glaviano, A, وآخرون
منشور في: (2023)

Trisubstituted-imidazoles induce apoptosis in human breast cancer cells by targeting the oncogenic PI3K/Akt/mTOR signaling pathway
بواسطة: Mohan C.D., وآخرون
منشور في: (2018)

Combination of metformin and 9-cis retinoic acid increases apoptosis in C6 glioma stem-like cells
بواسطة: Chanchai Songthaveesin, وآخرون
منشور في: (2019)

Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma
بواسطة: Moore, N.F, وآخرون
منشور في: (2020)

Plumbagin Suppresses Breast Cancer Progression by Downregulating HIF-1α Expression via a PI3K/Akt/mTOR Independent Pathway under Hypoxic Condition
بواسطة: Jampasri S.
منشور في: (2023)

Brassinin represses invasive potential of lung carcinoma cells through deactivation of PI3K/Akt/mTOR signaling cascade
بواسطة: Yang, M.H., وآخرون
منشور في: (2021)

Hypaphorine attenuates lipopolysaccharide-induced endothelial inflammation via regulation of TLR4 and PPAR-γ dependent on PI3K/Akt/mTOR signal pathway
بواسطة: Sun, H, وآخرون
منشور في: (2020)

Holothuria scabra Extract Induces Cell Apoptosis and Suppresses Warburg Effect by Down-Regulating Akt/mTOR/HIF-1 Axis in MDA-MB-231 Breast Cancer Cells
بواسطة: Laphatrada Yurasakpong, وآخرون
منشور في: (2020)

PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell lines
بواسطة: Que, J., وآخرون
منشور في: (2011)

Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression
بواسطة: Wu, M, وآخرون
منشور في: (2020)

mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif
بواسطة: Wu, Y.-T., وآخرون
منشور في: (2014)

Molecular mechanisms of tumor resistance to PI3K-mTOR-targeted therapy
بواسطة: Tan, J., وآخرون
منشور في: (2014)

Microalga Chlorella sp. extract induced apoptotic cell death of cholangiocarcinoma via AKT/mTOR signaling pathway
بواسطة: Sawasdee N.
منشور في: (2023)

Microalga Chlorella sp. extract induced apoptotic cell death of cholangiocarcinoma via AKT/mTOR signaling pathway
بواسطة: Sawasdee N.
منشور في: (2023)

Microalga Chlorella sp. extract induced apoptotic cell death of cholangiocarcinoma via AKT/mTOR signaling pathway
بواسطة: Sawasdee N.
منشور في: (2023)

mTOR, autophagy, and reprogramming
بواسطة: Tang, B.L
منشور في: (2020)

Epstein–Barr virus-encoded LMP1 induces ectopic CD137 expression on Hodgkin and Reed–Sternberg cells via the PI3K-AKT-mTOR pathway
بواسطة: SNEHA PRIYA ARAVINTH, وآخرون
منشور في: (2019)

Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling
بواسطة: Ruhainee Tohkayomatee, وآخرون
منشور في: (2022)

Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling
بواسطة: Tohkayomatee R.
منشور في: (2023)

Erianthridin suppresses non-small-cell lung cancer cell metastasis through inhibition of Akt/mTOR/p70<sup>S6K</sup> signaling pathway
بواسطة: Sutthaorn Pothongsrisit, وآخرون
منشور في: (2022)

Diallyl disulfide induces apoptosis and autophagy via mTOR pathway in myeloid leukemic cell line
بواسطة: Tanitta Suangtamai, وآخرون
منشور في: (2018)

Acquired resistance to PI3K/mTOR inhibition is associated with mitochondrial DNA mutation and glycolysis
بواسطة: Koh K.X., وآخرون
منشور في: (2020)

?-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
بواسطة: Siveen K.S., وآخرون
منشور في: (2020)

Synthetic naphthoquinone analogs as PI3K/AKT/m TOR targeted inhibitor
بواسطة: Adzkia Fasha
منشور في: (2023)

Casticin-induced inhibition of cell growth and survival are mediated through the dual modulation of Akt/mTOR signaling cascade
بواسطة: Lee, J.H., وآخرون
منشور في: (2022)

Nutrient starvation induces apoptosis and autophagy in C6 glioma stem-like cells
بواسطة: Wanna Sa-nongdej, وآخرون
منشور في: (2022)

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model
بواسطة: Siveen, K.S., وآخرون
منشور في: (2014)

α7-Nicotinic acetylcholine receptor antagonist QND7 suppresses non-small cell lung cancer cell proliferation and migration via inhibition of Akt/mTOR signaling
بواسطة: Wasita Witayateeraporn, وآخرون
منشور في: (2020)

EEF1A2 siRNA Suppresses MPP<sup>+</sup>-Induced Activation of Akt and mTOR and Potentiates Caspase-3 Activation in a Parkinson's Disease Model
بواسطة: Khwanraj K.
منشور في: (2023)

VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer
بواسطة: Hart, S., وآخرون
منشور في: (2016)

Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKC<inf>ζ</inf>or mTOR in TPO-dependent cell lines and primary megakaryocytes
بواسطة: Supantitra Chanprasert, وآخرون
منشور في: (2018)

Role of mTOR inhibitor in cholangiocarcinoma cell progression
بواسطة: Penpak Moolthiya, وآخرون
منشور في: (2018)

A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase
بواسطة: Zhou, J, وآخرون
منشور في: (2020)

An in vitro assay for the kinase activity of mTOR complex 2
بواسطة: Huang, J.
منشور في: (2016)

TIPE2 induced the proliferation, survival, and migration of lung cancer cells through modulation of AKt/mTOR/NF-κB signaling cascade
بواسطة: Bordoloi, D., وآخرون
منشور في: (2021)

SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
بواسطة: Seah, Kwi Shan, وآخرون
منشور في: (2023)

Roles of mTOR complex 2 in canonical Wnt signaling in glioblastoma.
بواسطة: Tankun Banlue
منشور في: (2022)