Uremia‐Induced Gut Barrier Defect in 5/6 Nephrectomized Mice Is Worsened by Candida Administration through a Synergy of Uremic Toxin, Lipopolysaccharide, and (1à3)‐β‐D‐ Glucan, but Is Attenuated by Lacticaseibacillus rhamnosus L34

• Main Authors: Somkanya Tungsanga, Wimonrat Panpetch, Thansita Bhunyakarnjanarat, Kanyarat Udompornpitak, Pisut Katavetin, Wiwat Chancharoenthana, Piraya Chatthanathon, Naraporn Somboonna, Kriang Tungsanga, Somying Tumwasorn, Asada Leelahavanichkul
• 其他作者: Faculty of Tropical Medicine, Mahidol University
• 格式: Article
• 出版: 2022
• 主題: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Computer Science
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/73404

A chronic kidney disease (CKD) causes uremic toxin accumulation and gut dysbiosis, which further induces gut leakage and worsening CKD. Lipopolysaccharide (LPS) of Gram‐negative bacteria and (1à3)‐β‐D‐glucan (BG) of fungi are the two most abundant gut microbial molecules. Due to limited data on the...