Practical Laboratory Tools for Monitoring of BCR-ABL1 Transcripts and Tyrosine Kinase (TK) Domain Mutations in Chronic Myeloid Leukemia Patients Undergoing TK Inhibitor Therapy: A Single-Center Experience in Thailand

• المؤلفون الرئيسيون: Nittaya Limsuwanachot, Adcharee Kongruang, Budsaba Rerkamnuaychoke, Roongrudee Singdong, Pimjai Niparuck, Saengsuree Jootar, Teerapong Siriboonpiputtana
• مؤلفون آخرون: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• التنسيق: مقال
• منشور في: 2020
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Medicine
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/57705
• المؤسسة: Mahidol University

OBJECTIVE: The genetic hallmark of CML is known as the appearance of t(9;22)(q34.1;q11.2) (BCR-ABL1) which is present in more than 95% of cases. Here, we demonstrated practical laboratory tools for monitoring of BCR-ABL1 transcripts in chronic myeloid leukemia patients undergoing TK inhibitor therap...