Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children

• Main Authors: Wiparat Manuyakorn, Plernpit Likkasittipan, Sukanya Wattanapokayakit, Supharat Suvichapanich, Wimala Inunchot, Nuanjun Wichukchinda, Chaiyos Khongkhatithuml, Lunliya Thampratankul, Wasu Kamchaisatian, Suwat Benjaponpitak, Surakameth Mahasirimongkol
• 其他作者: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• 格式: Article
• 出版: 2020
• 主題: Medicine; Neuroscience
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/54595

© 2020 Elsevier B.V. Purpose: Phenytoin (PHT) is a common causative drug for severe cutaneous adverse drug reactions (SCARs) in children. SCARs, including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are associate...