Burkholderia pseudomallei acquired ceftazidime resistance due to gene duplication and amplification

© 2019 Elsevier Ltd Ceftazidime (CAZ) is the antibiotic of choice for the treatment of Burkholderia pseudomallei infection (melioidosis). The chromosomally-encoded PenA β-lactamase possesses weak cephalosporinase activity. The wild-type penA gene confers clinically significant CAZ resistance only wh...

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Bibliographic Details
Main Authors: Sunisa Chirakul, Nawarat Somprasong, Michael H. Norris, Vanaporn Wuthiekanun, Narisara Chantratita, Apichai Tuanyok, Herbert P. Schweizer
Other Authors: University of Florida
Format: Article
Published: 2020
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/51672
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Institution: Mahidol University