A three-dimensional organoid model recapitulates tumorigenic aspects and drug responses of advanced human retinoblastoma

• Main Authors: Duangporn Saengwimol, Duangnate Rojanaporn, Vijender Chaitankar, Pamorn Chittavanich, Rangsima Aroonroch, Tatpong Boontawon, Weerin Thammachote, Natini Jinawath, Suradej Hongeng, Rossukon Kaewkhaw
• Other Authors: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• Format: Article
• Published: 2019
• Subjects: Multidisciplinary
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/47474

© 2018, The Author(s). Persistent or recurrent retinoblastoma (RB) is associated with the presence of vitreous or/and subretinal seeds in advanced RB and represents a major cause of therapeutic failure. This necessitates the development of novel therapies and thus requires a model of advanced RB for...