Copper/Persulfate-Promoted Oxidative Decarboxylative C−H Acylation of Pyrazolones with α-Oxocarboxylic Acids: Direct Access to 4-Acylpyrazolones under Mild Conditions

© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim A facile and efficient oxidative C−H acylation of N-substituted pyrazolones using α-oxocarboxylic acids as an acyl group source was developed. A combination of Cu(OAc)2 and K2S2O8 enables the reaction to proceed smoothly under air and provides...

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Bibliographic Details
Main Authors: Tanakorn Kittikool, Akkharaphong Thupyai, Khamphee Phomphrai, Sirilata Yotphan
Other Authors: Vidyasirimedhi Institute of Science and Technology
Format: Article
Published: 2019
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/45419
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