Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort

© 2018 Background: Frailty is a clinical state of increased vulnerability from aging-associated decline. We aimed to determine if a Thai Frailty Index predicted all-cause mortality in community-dwelling older Thais when accounting for age, gender and socioeconomic status. Methods: Data of 8195 subje...

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Main Authors: V. Srinonprasert, C. Chalermsri, W. Aekplakorn
其他作者: Mahidol University
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出版: 2019
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spelling th-mahidol.451122019-08-28T14:04:50Z Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort V. Srinonprasert C. Chalermsri W. Aekplakorn Mahidol University Faculty of Medicine, Siriraj Hospital, Mahidol University Biochemistry, Genetics and Molecular Biology Medicine Nursing Social Sciences © 2018 Background: Frailty is a clinical state of increased vulnerability from aging-associated decline. We aimed to determine if a Thai Frailty Index predicted all-cause mortality in community-dwelling older Thais when accounting for age, gender and socioeconomic status. Methods: Data of 8195 subjects aged 60 years and over from the Fourth Thai National Health Examination Survey were used to create the Thai Frailty Index by calculating the ratio of accumulated deficits using a cut-off point of 0.25 to define frailty. The associations were explored using Cox proportional hazard models. Results: The mean age of participants was 69.2 years (SD 6.8). The prevalence of frailty was 22.1%. The Thai Frailty Index significantly predicted mortality (hazard ratio = 2.34, 95% CI 2.10–2.61, p < 0.001). The association between frailty and mortality was stronger in males (hazard ratio = 2.71, 95% CI 2.33–3.16). Higher wealth status had a protective effect among non-frail older adults but not among frail ones. Conclusions: In community-dwelling older Thai adults, the Thai Frailty Index demonstrated a high prevalence of frailty and predicted mortality. Frail older Thai adults did not earn the protective effect of reducing mortality with higher socioeconomic status. Maintaining health rather than accumulating wealth may be better for a longer healthier life for older people in middle income countries. 2019-08-23T10:31:07Z 2019-08-23T10:31:07Z 2018-07-01 Article Archives of Gerontology and Geriatrics. Vol.77, (2018), 124-128 10.1016/j.archger.2018.05.002 18726976 01674943 2-s2.0-85046670436 https://repository.li.mahidol.ac.th/handle/123456789/45112 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85046670436&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
Nursing
Social Sciences
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Nursing
Social Sciences
V. Srinonprasert
C. Chalermsri
W. Aekplakorn
Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort
description © 2018 Background: Frailty is a clinical state of increased vulnerability from aging-associated decline. We aimed to determine if a Thai Frailty Index predicted all-cause mortality in community-dwelling older Thais when accounting for age, gender and socioeconomic status. Methods: Data of 8195 subjects aged 60 years and over from the Fourth Thai National Health Examination Survey were used to create the Thai Frailty Index by calculating the ratio of accumulated deficits using a cut-off point of 0.25 to define frailty. The associations were explored using Cox proportional hazard models. Results: The mean age of participants was 69.2 years (SD 6.8). The prevalence of frailty was 22.1%. The Thai Frailty Index significantly predicted mortality (hazard ratio = 2.34, 95% CI 2.10–2.61, p < 0.001). The association between frailty and mortality was stronger in males (hazard ratio = 2.71, 95% CI 2.33–3.16). Higher wealth status had a protective effect among non-frail older adults but not among frail ones. Conclusions: In community-dwelling older Thai adults, the Thai Frailty Index demonstrated a high prevalence of frailty and predicted mortality. Frail older Thai adults did not earn the protective effect of reducing mortality with higher socioeconomic status. Maintaining health rather than accumulating wealth may be better for a longer healthier life for older people in middle income countries.
author2 Mahidol University
author_facet Mahidol University
V. Srinonprasert
C. Chalermsri
W. Aekplakorn
format Article
author V. Srinonprasert
C. Chalermsri
W. Aekplakorn
author_sort V. Srinonprasert
title Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort
title_short Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort
title_full Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort
title_fullStr Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort
title_full_unstemmed Frailty index to predict all-cause mortality in Thai community-dwelling older population: A result from a National Health Examination Survey cohort
title_sort frailty index to predict all-cause mortality in thai community-dwelling older population: a result from a national health examination survey cohort
publishDate 2019
url https://repository.li.mahidol.ac.th/handle/123456789/45112
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