A proteasome inhibitor produced by Burkholderia pseudomallei modulates intracellular growth

• Main Authors: Sariqa Wagley, Muthita Vanaporn, Darawan Rinchai, Laura Conejero, Ganjana Lertmemongkolchai, Gregory J. Bancroft, Richard W. Titball
• Other Authors: University of Exeter
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/42835
• Institution: Mahidol University

© 2017 Elsevier Ltd The NRPS/PKS cluster encodes the enzymes necessary for glidobactin synthesis it is partially conserved in various members of the Burkholderia genus including B. pseudomallei. In this study we have shown that the insertional inactivation or deletion of glbC in this cluster in B. p...