A stereoselective approach to bioactive secolignans: Synthesis of peperomin C and its analogues

• المؤلفون الرئيسيون: Darunee Soorukram, Jaray Panmuang, Patoomratana Tuchinda, Chutima Kuhakarn, Vichai Reutrakul, Manat Pohmakotr
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/33217

© 2014 Elsevier Ltd. All rights reserved. A stereoselective approach to secolignans is described. The key synthetic strategy involves an asymmetric aldol reaction to control the creation of the stereogenic center at the β-carbon of the target secolignans. In the present work, peperomin C and its ana...