A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives

A practical protocol for the one-pot synthesis of N-substituted 2-aminoazole derivatives is described, employing simple azole substrates, nitrogen nucleophiles, lithium tert-butoxide as the base, and iodine to mediate carbon-nitrogen bond formation. This method proceeds at room temperature under an...

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Main Authors: Sirilata Yotphan, Danupat Beukeaw, Vichai Reutrakul
其他作者: Mahidol University
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出版: 2018
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spelling th-mahidol.314842018-10-19T11:49:00Z A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives Sirilata Yotphan Danupat Beukeaw Vichai Reutrakul Mahidol University Chemical Engineering Chemistry A practical protocol for the one-pot synthesis of N-substituted 2-aminoazole derivatives is described, employing simple azole substrates, nitrogen nucleophiles, lithium tert-butoxide as the base, and iodine to mediate carbon-nitrogen bond formation. This method proceeds at room temperature under an air atmosphere using a normal benchtop set-up, or can be performed conveniently using microwave irradiation. © Georg Thieme Verlag Stuttgart - New York. 2018-10-19T04:45:52Z 2018-10-19T04:45:52Z 2013-03-11 Article Synthesis (Germany). Vol.45, No.7 (2013), 936-942 10.1055/s-0032-1316868 1437210X 00397881 2-s2.0-84875235620 https://repository.li.mahidol.ac.th/handle/123456789/31484 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875235620&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Chemical Engineering
Chemistry
spellingShingle Chemical Engineering
Chemistry
Sirilata Yotphan
Danupat Beukeaw
Vichai Reutrakul
A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives
description A practical protocol for the one-pot synthesis of N-substituted 2-aminoazole derivatives is described, employing simple azole substrates, nitrogen nucleophiles, lithium tert-butoxide as the base, and iodine to mediate carbon-nitrogen bond formation. This method proceeds at room temperature under an air atmosphere using a normal benchtop set-up, or can be performed conveniently using microwave irradiation. © Georg Thieme Verlag Stuttgart - New York.
author2 Mahidol University
author_facet Mahidol University
Sirilata Yotphan
Danupat Beukeaw
Vichai Reutrakul
format Article
author Sirilata Yotphan
Danupat Beukeaw
Vichai Reutrakul
author_sort Sirilata Yotphan
title A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives
title_short A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives
title_full A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives
title_fullStr A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives
title_full_unstemmed A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives
title_sort convenient one-pot synthesis of n-substituted 2-aminoazole derivatives
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/31484
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