A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives
A practical protocol for the one-pot synthesis of N-substituted 2-aminoazole derivatives is described, employing simple azole substrates, nitrogen nucleophiles, lithium tert-butoxide as the base, and iodine to mediate carbon-nitrogen bond formation. This method proceeds at room temperature under an...
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th-mahidol.314842018-10-19T11:49:00Z A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives Sirilata Yotphan Danupat Beukeaw Vichai Reutrakul Mahidol University Chemical Engineering Chemistry A practical protocol for the one-pot synthesis of N-substituted 2-aminoazole derivatives is described, employing simple azole substrates, nitrogen nucleophiles, lithium tert-butoxide as the base, and iodine to mediate carbon-nitrogen bond formation. This method proceeds at room temperature under an air atmosphere using a normal benchtop set-up, or can be performed conveniently using microwave irradiation. © Georg Thieme Verlag Stuttgart - New York. 2018-10-19T04:45:52Z 2018-10-19T04:45:52Z 2013-03-11 Article Synthesis (Germany). Vol.45, No.7 (2013), 936-942 10.1055/s-0032-1316868 1437210X 00397881 2-s2.0-84875235620 https://repository.li.mahidol.ac.th/handle/123456789/31484 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875235620&origin=inward |
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Chemical Engineering Chemistry Sirilata Yotphan Danupat Beukeaw Vichai Reutrakul A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives |
description |
A practical protocol for the one-pot synthesis of N-substituted 2-aminoazole derivatives is described, employing simple azole substrates, nitrogen nucleophiles, lithium tert-butoxide as the base, and iodine to mediate carbon-nitrogen bond formation. This method proceeds at room temperature under an air atmosphere using a normal benchtop set-up, or can be performed conveniently using microwave irradiation. © Georg Thieme Verlag Stuttgart - New York. |
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Mahidol University |
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Mahidol University Sirilata Yotphan Danupat Beukeaw Vichai Reutrakul |
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Article |
author |
Sirilata Yotphan Danupat Beukeaw Vichai Reutrakul |
author_sort |
Sirilata Yotphan |
title |
A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives |
title_short |
A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives |
title_full |
A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives |
title_fullStr |
A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives |
title_full_unstemmed |
A convenient one-pot synthesis of N-substituted 2-aminoazole derivatives |
title_sort |
convenient one-pot synthesis of n-substituted 2-aminoazole derivatives |
publishDate |
2018 |
url |
https://repository.li.mahidol.ac.th/handle/123456789/31484 |
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1763489517426180096 |