Fluoride-catalyzed nucleophilic addition of PhSCF<inf>2</inf>SiMe <inf>3</inf> to anhydrides: Synthesis of γ-difluoromethylated γ-lactams

PhSCF<inf>2</inf>SiMe<inf>3</inf> (1) underwent fluoride-catalyzed nucleophilic addition to the carbonyl group of anhydrides to provide the corresponding γ-difluoro(phenylsulfanyl)methyl γ-lactols, which were employed for the synthesis of γ-difluoromethylated γ-lactams. © 201...

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Bibliographic Details
Main Authors: Vannapha Pharikronburee, Teerachai Punirun, Darunee Soorukram, Chutima Kuhakarn, Patoomratana Tuchinda, Vichai Reutrakul, Manat Pohmakotr
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31344
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