Fluoride-catalyzed nucleophilic addition of PhSCF<inf>2</inf>SiMe <inf>3</inf> to anhydrides: Synthesis of γ-difluoromethylated γ-lactams

Fluoride-catalyzed nucleophilic addition of PhSCF<inf>2</inf>SiMe <inf>3</inf> to anhydrides: Synthesis of γ-difluoromethylated γ-lactams

PhSCF<inf>2</inf>SiMe<inf>3</inf> (1) underwent fluoride-catalyzed nucleophilic addition to the carbonyl group of anhydrides to provide the corresponding γ-difluoro(phenylsulfanyl)methyl γ-lactols, which were employed for the synthesis of γ-difluoromethylated γ-lactams. © 201...

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Main Authors: Vannapha Pharikronburee, Teerachai Punirun, Darunee Soorukram, Chutima Kuhakarn, Patoomratana Tuchinda, Vichai Reutrakul, Manat Pohmakotr
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Chemistry
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31344
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spelling th-mahidol.313442018-10-19T11:48:45Z Fluoride-catalyzed nucleophilic addition of PhSCF&lt;inf&gt;2&lt;/inf&gt;SiMe &lt;inf&gt;3&lt;/inf&gt; to anhydrides: Synthesis of γ-difluoromethylated γ-lactams Vannapha Pharikronburee Teerachai Punirun Darunee Soorukram Chutima Kuhakarn Patoomratana Tuchinda Vichai Reutrakul Manat Pohmakotr Mahidol University Biochemistry, Genetics and Molecular Biology Chemistry PhSCF<inf>2</inf>SiMe<inf>3</inf> (1) underwent fluoride-catalyzed nucleophilic addition to the carbonyl group of anhydrides to provide the corresponding γ-difluoro(phenylsulfanyl)methyl γ-lactols, which were employed for the synthesis of γ-difluoromethylated γ-lactams. © 2013 The Royal Society of Chemistry. 2018-10-19T04:40:39Z 2018-10-19T04:40:39Z 2013-03-28 Article Organic and Biomolecular Chemistry. Vol.11, No.12 (2013), 2022-2033 10.1039/c3ob27193e 14770520 2-s2.0-84876719100 https://repository.li.mahidol.ac.th/handle/123456789/31344 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84876719100&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
Chemistry
spellingShingle Biochemistry, Genetics and Molecular Biology
Chemistry
Vannapha Pharikronburee
Teerachai Punirun
Darunee Soorukram
Chutima Kuhakarn
Patoomratana Tuchinda
Vichai Reutrakul
Manat Pohmakotr
Fluoride-catalyzed nucleophilic addition of PhSCF&lt;inf&gt;2&lt;/inf&gt;SiMe &lt;inf&gt;3&lt;/inf&gt; to anhydrides: Synthesis of γ-difluoromethylated γ-lactams
description PhSCF<inf>2</inf>SiMe<inf>3</inf> (1) underwent fluoride-catalyzed nucleophilic addition to the carbonyl group of anhydrides to provide the corresponding γ-difluoro(phenylsulfanyl)methyl γ-lactols, which were employed for the synthesis of γ-difluoromethylated γ-lactams. © 2013 The Royal Society of Chemistry.
author2 Mahidol University
author_facet Mahidol University
Vannapha Pharikronburee
Teerachai Punirun
Darunee Soorukram
Chutima Kuhakarn
Patoomratana Tuchinda
Vichai Reutrakul
Manat Pohmakotr
format Article
author Vannapha Pharikronburee
Teerachai Punirun
Darunee Soorukram
Chutima Kuhakarn
Patoomratana Tuchinda
Vichai Reutrakul
Manat Pohmakotr
author_sort Vannapha Pharikronburee
title Fluoride-catalyzed nucleophilic addition of PhSCF&lt;inf&gt;2&lt;/inf&gt;SiMe &lt;inf&gt;3&lt;/inf&gt; to anhydrides: Synthesis of γ-difluoromethylated γ-lactams
title_short Fluoride-catalyzed nucleophilic addition of PhSCF&lt;inf&gt;2&lt;/inf&gt;SiMe &lt;inf&gt;3&lt;/inf&gt; to anhydrides: Synthesis of γ-difluoromethylated γ-lactams
title_full Fluoride-catalyzed nucleophilic addition of PhSCF&lt;inf&gt;2&lt;/inf&gt;SiMe &lt;inf&gt;3&lt;/inf&gt; to anhydrides: Synthesis of γ-difluoromethylated γ-lactams
title_fullStr Fluoride-catalyzed nucleophilic addition of PhSCF&lt;inf&gt;2&lt;/inf&gt;SiMe &lt;inf&gt;3&lt;/inf&gt; to anhydrides: Synthesis of γ-difluoromethylated γ-lactams
title_full_unstemmed Fluoride-catalyzed nucleophilic addition of PhSCF&lt;inf&gt;2&lt;/inf&gt;SiMe &lt;inf&gt;3&lt;/inf&gt; to anhydrides: Synthesis of γ-difluoromethylated γ-lactams
title_sort fluoride-catalyzed nucleophilic addition of phscf&lt;inf&gt;2&lt;/inf&gt;sime &lt;inf&gt;3&lt;/inf&gt; to anhydrides: synthesis of γ-difluoromethylated γ-lactams
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/31344
_version_ 1763491225070993408

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