A new method for the synthesis of 2-phenylsulfonylaziridines via the reaction of α-halosulfonyl carbanion to imines

• المؤلفون الرئيسيون: Vichai Reutrakul, Vichukorn Prapansiri, Chitchanun Panyachotipun
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/30577

The reaction of lithio α-chloromethyl phenyl sulfone with imines gave aziridines in good yields. The resulting aziridines were alkylated and underwent the 1,3-dipolar cycloaddition with dimethylacetylene dicarboxylate to give pyrroles in excellent yields. © 1984.