Urokinase receptor is necessary for bacterial defense against pneumonia-derived septic melioidosis by facilitating phagocytosis

• المؤلفون الرئيسيون: W. Joost Wiersinga, Liesbeth M. Kager, Joppe W.R. Hovius, Gerritje J.W. Van Der Windt, Alex F. De Vos, Joost C.M. Meijers, Joris J. Roelofs, Arjen Dondorp, Marcel Levi, Nicholas P. Day, Sharon J. Peacock, Tom Van Der Poll
• مؤلفون آخرون: Academic Medical Centre, University of Amsterdam
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Immunology and Microbiology
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/29250

Urokinase receptor (urokinase-type plasminogen activator receptor [uPAR], CD87), a GPI-anchored protein, is considered to play an important role in inflammation and fibrinolysis. The Gram-negative bacterium Burkholderia pseudomallei is able to survive and replicate within leukocytes and causes melio...