Anti-HIV1 Diterpenoids from Leaves and Twigs of Polyalthia sclerophylla

• Main Authors: Siriporn Saepou, Manat Pohmakotr, Vichai Reutrakul, Chalobon Yoosook, Jitra Kasisit, Chanita Napaswad, Patoomratana Tuchinda
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28710

Bioassay-guided fractionation and purification of the anti-HIV-1-active MeOH extract from the leaves and twigs of Polyalthia sclerophylla led to the isolation of two new compounds, ent-kaur-sclerodimer (1) and cyclotucanol 3-palmitate (2), along with the known ent-kaur-16-en-19-oic acid (3), 15-hydr...