A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population

• Main Authors: Izumi Naka, Jintana Patarapotikul, Katsushi Tokunaga, Hathairad Hananantachai, Naoyuki Tsuchiya, Jun Ohashi
• 其他作者: University of Tsukuba
• 格式: Article
• 出版: 2018
• 主題: Immunology and Microbiology; Medicine
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/27618
• 機構: Mahidol University

Background. Interleukin-12 (IL-12), a heterodimeric cytokine composed of p35 and p40 subunits, has been thought to play an important role in the pathogenesis of malaria. The IL-12p40 subunit is encoded by the IL12B gene. An IL12B promoter allele, CTCTAA, at rs17860508 has been reported to be associa...