Responses of primary human nasal epithelial cells to EDIII-DENV stimulation: the first step to intranasal dengue vaccination

• Main Authors: Nattika Nantachit, Panya Sunintaboon, Sukathida Ubol
• Other Authors: Mahidol University. Faculty of Science. Department of Microbiology
• Format: Article
• Language: English
• Published: 2017
• Subjects: Open Access article; Domain III of dengue virus; Trimethyl chitosan nanoparticles; Nasal stimulation; Dengue vaccine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/2744
• Institution: Mahidol University

Background: About half of the world’s population are living in the endemic area of dengue viruses implying that a rapid-mass vaccination may be required. In addition, a major target of dengue vaccine are children, thus, a needle-free administration is more attractive. These problems may be overcom...