Mefloquine concentration profiles during prophylactic dose regimens

• المؤلفون الرئيسيون: Herwig Kollaritsch, Juntra Karbwang, Gerhard Wiedermann, Andrea Mikolasek, Kesara Na-Bangchang, Walter H. Wernsdorfer
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Medicine
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/26243

A pharmacokinetic study with (malaria) prophylactic doses of mefloquine hydrochloride was conducted in 12 healthy adult subjects (Caucasians), 6 females and 6 males, mean age 29.2 ± 6.4 years, mean weight 70.6 ± 13.4 kg. Doses of 250 mg mefloquine were administered on days 0, 1, 7, 14, 21 and 28. Si...