Comparative quantitative structure-activity study of radical scavengers

• المؤلفون الرئيسيون: Opa Vajragupta, Preecha Boonchoong, Yuvadee Wongkrajang
• مؤلفون آخرون: Mahidol University
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/25850

Classic and three-dimensional (3-D) QSAR analyses of 13 radical scavengers (1-13) were performed to derive two classic, two Apex-3-D and one comparative field analysis (CoMFA) models. Two classical models with predictive cross-validated r2(Q2) over 0.96 indicated that the activity was attributed to...