Efficacy and safety of dihydroartemisinin-piperaquine
Dihydroartemisinin-piperaquine, a fixed-dose combination antimalarial, is an inexpensive, safe and highly effective treatment for uncomplicated falciparum or vivax malaria. Efficacy assessed over 28-63 days has consistently exceeded 95% in the treatment of multidrug-resistant falciparum malaria. Mor...
Saved in:
| Main Authors: | , , , , |
|---|---|
| 其他作者: | |
| 格式: | Review |
| 出版: |
2018
|
| 主題: | |
| 在線閱讀: | https://repository.li.mahidol.ac.th/handle/123456789/24519 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
| 機構: | Mahidol University |
| id |
th-mahidol.24519 |
|---|---|
| record_format |
dspace |
| spelling |
th-mahidol.245192018-08-24T09:01:48Z Efficacy and safety of dihydroartemisinin-piperaquine H. Y. Myint E. A. Ashley N. P J Day F. Nosten N. J. White Mahidol University Epicentre Churchill Hospital Shoklo Malaria Research Unit Immunology and Microbiology Medicine Dihydroartemisinin-piperaquine, a fixed-dose combination antimalarial, is an inexpensive, safe and highly effective treatment for uncomplicated falciparum or vivax malaria. Efficacy assessed over 28-63 days has consistently exceeded 95% in the treatment of multidrug-resistant falciparum malaria. More than 2600 patients have been treated with this combination in prospective studies, mainly in Southeast Asia. Tolerability was uniformly good, and no serious adverse effects have been identified. The dosing regimen has been simplified from four doses to once daily over 3 days. More information on efficacy in Africa, and more pharmacokinetic and efficacy data in children are needed. © 2007 Royal Society of Tropical Medicine and Hygiene. 2018-08-24T01:52:07Z 2018-08-24T01:52:07Z 2007-09-01 Review Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.101, No.9 (2007), 858-866 10.1016/j.trstmh.2007.05.018 00359203 2-s2.0-34447617873 https://repository.li.mahidol.ac.th/handle/123456789/24519 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34447617873&origin=inward |
| institution |
Mahidol University |
| building |
Mahidol University Library |
| continent |
Asia |
| country |
Thailand Thailand |
| content_provider |
Mahidol University Library |
| collection |
Mahidol University Institutional Repository |
| topic |
Immunology and Microbiology Medicine |
| spellingShingle |
Immunology and Microbiology Medicine H. Y. Myint E. A. Ashley N. P J Day F. Nosten N. J. White Efficacy and safety of dihydroartemisinin-piperaquine |
| description |
Dihydroartemisinin-piperaquine, a fixed-dose combination antimalarial, is an inexpensive, safe and highly effective treatment for uncomplicated falciparum or vivax malaria. Efficacy assessed over 28-63 days has consistently exceeded 95% in the treatment of multidrug-resistant falciparum malaria. More than 2600 patients have been treated with this combination in prospective studies, mainly in Southeast Asia. Tolerability was uniformly good, and no serious adverse effects have been identified. The dosing regimen has been simplified from four doses to once daily over 3 days. More information on efficacy in Africa, and more pharmacokinetic and efficacy data in children are needed. © 2007 Royal Society of Tropical Medicine and Hygiene. |
| author2 |
Mahidol University |
| author_facet |
Mahidol University H. Y. Myint E. A. Ashley N. P J Day F. Nosten N. J. White |
| format |
Review |
| author |
H. Y. Myint E. A. Ashley N. P J Day F. Nosten N. J. White |
| author_sort |
H. Y. Myint |
| title |
Efficacy and safety of dihydroartemisinin-piperaquine |
| title_short |
Efficacy and safety of dihydroartemisinin-piperaquine |
| title_full |
Efficacy and safety of dihydroartemisinin-piperaquine |
| title_fullStr |
Efficacy and safety of dihydroartemisinin-piperaquine |
| title_full_unstemmed |
Efficacy and safety of dihydroartemisinin-piperaquine |
| title_sort |
efficacy and safety of dihydroartemisinin-piperaquine |
| publishDate |
2018 |
| url |
https://repository.li.mahidol.ac.th/handle/123456789/24519 |
| _version_ |
1763491222189506560 |