Phase transfer bioconversion of penicillin G into 6-APA by immobilized penicillin acylase in recycling aqueous two-phase systems with a light-sensitive copolymer

• المؤلفون الرئيسيون: Ke Ming Jin, Xue Jun Cao, Ying Ping Zhuang, Ju Chu, Si Liang Zhang, Duerasor Orawan
• مؤلفون آخرون: East China University of Science and Technology
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Chemical Engineering; Engineering; Materials Science
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/24315
• المؤسسة: Mahidol University

Immobilized penicillin acylase was used for bioconversion of penicillin G into 6-APA in aqueous two-phase systems consisted of a light-sensitive polymer (PNBC 300000) and Dextran 20000. Partition coefficients of 6-APA was found to be about 8.4 in the presence of 50 mmol/L KCl. Results of enzyme kine...