Stereoselective synthesis of β-carboethoxy-γ-lactams via imino Mukaiyama aldol-type reaction of 1,4-bis(trimethylsilyloxy)-1,4-diethoxy-1,3-butadiene

Stereoselective synthesis of β-carboethoxy-γ-lactams via imino Mukaiyama aldol-type reaction of 1,4-bis(trimethylsilyloxy)-1,4-diethoxy-1,3-butadiene

The reaction of the (bis)trimethylsilyloxy derivative of diethyl succinate with imines in the presence of ZnCl2provides a general stereoselective entry to β-carboethoxy-γ-lactams. © 2007 Elsevier Ltd. All rights reserved.

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Bibliographic Details
Main Authors: Manat Pohmakotr, Nattawut Yotapan, Patoomratana Tuchinda, Chutima Kuhakarn, Vichai Reutrakul
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Chemistry
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24197
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https://repository.li.mahidol.ac.th/handle/123456789/24197

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