Stereoselective synthesis of β-carboethoxy-γ-lactams via imino Mukaiyama aldol-type reaction of 1,4-bis(trimethylsilyloxy)-1,4-diethoxy-1,3-butadiene

• Main Authors: Manat Pohmakotr, Nattawut Yotapan, Patoomratana Tuchinda, Chutima Kuhakarn, Vichai Reutrakul
• 其他作者: Mahidol University
• 格式: Article
• 出版: 2018
• 主題: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• 在線閱讀: https://repository.li.mahidol.ac.th/handle/123456789/24197

The reaction of the (bis)trimethylsilyloxy derivative of diethyl succinate with imines in the presence of ZnCl2provides a general stereoselective entry to β-carboethoxy-γ-lactams. © 2007 Elsevier Ltd. All rights reserved.