General strategy for stereoselective synthesis of 1-substituted Exo,Endo-2,6-diaryl-3,7-dioxabicyclo[3.3.0]octanes: Total synthesis of (±)-gmelinol

• Main Authors: Manat Pohmakotr, Attapol Pinsa, Tipwan Mophuang, Patoomratana Tuchinda, Samran Prabpai, Palangpon Kongsaeree, Vichai Reutrakul
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23182

A general strategy for stereoselective synthesis of 1-substituted exo,endo-2,6-diaryl-3,7-dioxabicyclo[3.3.0]octanes including (±)-gmelinol from (2,3-trans)-(4,5-cis)-α-aroylparaconic esters, which are readily obtained from the reaction of vicinal dianions derived from α- aroylsuccinic esters with a...