Prenylated xanthones as potential antiplasmodial substances

• Main Authors: Wilawan Mahabusarakam, Kunnika Kuaha, Prapon Wilairat, Walter C. Taylor
• Other Authors: Prince of Songkla University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/23002

Mangostin, the major xanthone of Garcinia mangostana, and a series of synthetic derivatives were investigated for their in vitro antiplasmodial activity against Plasmodium falciparum. Mangostin itself showed moderate activity, but prenylated xanthones containing alkylamino functional groups exhibite...